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Antigenic Specificity | SET9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | neat |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Set9 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with Set8 from species other than human not tested. Set9 is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deacetylation of H3 by the NuRD complex and impairs Suv39h1-mediated methylation of H3K9. Set9 also methylates the tumor suppressor p53 at lysine 372, thereby enhancing its stability. IT contains a SET domain but lacks the pre- and post-SET domains. Anti-Set9 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling. |
Immunogen | Anti-SET9 Antibody was produced in rabbits by repeated immunizations with a recombinant protein of human Set9. |
Other Names | Histone-lysine N-methyltransferase SETD7, Histone H3-K4 methyltransferase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET 7/9, H3-K4-HMTase SETD7 |
Gene, Accession # | SETD7, Gene ID: 80854, NCBI: NP_085151.1, UniProt: Q8WTS6 |
Catalog # | 100-401-V83 |
Price | $445 |
Order / More Info | SET9 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |