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Antigenic Specificity | Pancortin |
Clone | S96-7 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | Immunohistochemistry, IF Microscopy, Immunoprecipitation, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Pancortin Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Pancortin from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Pancortin from other sources has not been determined. Neuroscience research. Pancortin, a member of a diverse family of secreted glycoproteins, is implicated in the development of the nervous system, and the glaucoma-associated protein myocilin. Studies suggest that Pancortin-2 interact with WAVE1 in a novel cell death cascade in adult, but not embryonic, cerebral cortical neurons. Specifically pancortin-2 is a mediator of ischemia-induced apoptosis of neurons in the adult cerebral cortex, and functions in a novel mitochondrial/actin associated protein complex that sequesters Bcl-xL. It is also involved in the generation of neural crest cells, and in neurogenesis. |
Immunogen | Pancortin Antibody was produced in mice by repeated immunizations raised against a synthetic peptide corresponding to an internal region of human pancortin-1. |
Other Names | Noelin, AMY, Noe1, Olfm1, Olfactomedin1, Neuronal olfactomedin-related ER localized protein, Pancortin |
Gene, Accession # | OLFM1, Gene ID: 10439, NCBI: NP_001269540.1, UniProt: Q99784 |
Catalog # | 200-301-G28 |
Price | $485 |
Order / More Info | Pancortin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |