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Antigenic Specificity | ESR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-ESR1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. ESR1 antibody is human, mouse and rat reactive. Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors (1). Estrogen receptors, including ESR1, also known as ER-alpha and ESR2 (ER-beta), contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ESR1 is a widely expressed nuclear protein and serves as a strong activator of estrogen responsive genes (1,2). Phosphorylation of serines 104 and 106, located in the N-terminal transcription activation function-1 domain (AF-1), plays a large role in regulating ER alpha activity (3). |
Immunogen | Anti-ESR1 antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the internal region of human ESR1. |
Other Names | ESR1 Antibody, ER, ESR, Era, ESRA, ESTRR, NR3A1, Estrogen receptor, ER-alpha, ER |
Gene, Accession # | ESR1, Gene ID: 2099, NCBI: NP_001116214, UniProt: P03372 |
Catalog # | 600-401-BB9 |
Price | $475 |
Order / More Info | ESR1 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |