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Antigenic Specificity | LAR/PTPRF |
Clone | S165-38 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | biotin conjugate |
Size | 100 µg |
Concentration | 1mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-LAR/PTPRF Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests similarity with rat and mouse based on 97% homology with the immunizing sequence. In addition, the sequence was >80% identical to PTPRD and PTPRS, as well as >50% identical to PTPRM and PTPRK. PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from β-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function (1,2,3,4). Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa). Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide. Anti-PTPRF is ideal for researchers interested in Cell adhesion Cadherin-mediated cell adhesion pathways, PAK pathways, insulin resistance and ureterocele. |
Immunogen | Anti-LAR/PTPRF Antibody was produced in mice by repeated immunizations of a fusion peptide consisting of amino acids 1315-1607 of human LAR. |
Other Names | Receptor-type tyrosine-protein phosphatase F, Leukocyte antigen related (LAR), FLJ43335, FLJ45062, FLJ45567, LAR, LAR protein, LARFN5C, LARS, LCA homolog, Leukocyte antigen related (LAR) PTP receptor, Leukocyte antigen related tyrosine phosphatase, Leukocyte common antigen related |
Gene, Accession # | LAR/PTPRF, Gene ID: 5792, UniProt: P10586 |
Catalog # | 200-306-W57 |
Price | $495 |
Order / More Info | LAR/PTPRF Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |