CD19 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD19 |
| Clone | 1D3 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 100 µg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated CD19 Monoclonal Antibody was Protein G Purified and is directed against mouse CD19. Reactivity is observed against mouse CD19. Cross reactivity with CD19 from other sources has not been tested. CD19 is a member of the immunoglobulin superfamily with 556 amino acid and two immunoglobulin-like C2-type domains. As a cell surface protein, CD19 is known to form a complex with CD21, CD81 and CD225 in the membrane of mature B cells. A major function of CD100 is to assemble with the antigen receptor of B lymphocytes so as to decrease the threshold for antigen receptor dependent stimulation thus enhancing the specificity and sensitivity of B cells towards antigens. Thus CD19 is an important protein for B cell antigen receptor signaling and regulation and also acts as a specialized adaptor protein for the amplification of Src family needed for this purpose. Regulation of growth of B cells is a major function of CD19 and its expression is confined to only B lymphocytes and follicular dendritic cells of the hematopoietic system. Increased expression of CD19 induces the production of auto-antibody thus giving an insight to the regulatory role of CD19 in autoimmunity. Defects in CD19 are a cause of hypogammaglobulinemia. |
| Immunogen | Anti-CD19 Antibody (Monoclonal) was produced by repeated immunizations with mouse CD19 transfected cell line. |
| Other Names | B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19 |
| Gene, Accession # | Cd19, Gene ID: 12478, NCBI: NP_033974.2, UniProt: P25918 |
| Catalog # | 200-502-M72 |
| Price | $495 |
| Order / More Info | CD19 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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