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Antigenic Specificity | Munc18 Phospho S515 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | immunoaffinity purified, no preservative |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Phospho-Ser515 Munc18 Antibody is directed against Munc18 protein phosphorylated at S515. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated Munc18. Minimal reactivity occurs against non-phosphorylated Munc18. Reactivity against Munc18 occurs from rat sources. However, reactivity is also expected against bovine, canine, chicken, human, mouse, non-human primate, and Xenopus based on 100% sequence homology. Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin. Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex. The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein. Munc-18 pS515 Antibody is ideal for researchers interested in Cell Signaling, Neuroscience, Signal Transduction research. |
Immunogen | Anti-Phospho-Ser515 Munc18 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser515 of rat Munc18 conjugated to KLH. |
Other Names | Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B |
Gene, Accession # | Stxbp2, Gene ID: 81804, NCBI: NP_112388.1, UniProt: Q62753 |
Catalog # | 600-401-X16 |
Price | $475 |
Order / More Info | Munc18 Phospho S515 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |