Munc18 Phospho S515 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityMunc18 Phospho S515
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatimmunoaffinity purified, no preservative
Size100 µL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionAnti-Phospho-Ser515 Munc18 Antibody is directed against Munc18 protein phosphorylated at S515. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated Munc18. Minimal reactivity occurs against non-phosphorylated Munc18. Reactivity against Munc18 occurs from rat sources. However, reactivity is also expected against bovine, canine, chicken, human, mouse, non-human primate, and Xenopus based on 100% sequence homology. Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin. Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex. The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein. Munc-18 pS515 Antibody is ideal for researchers interested in Cell Signaling, Neuroscience, Signal Transduction research.
ImmunogenAnti-Phospho-Ser515 Munc18 Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser515 of rat Munc18 conjugated to KLH.
Other NamesSyntaxin-binding protein 2, Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B
Gene, Accession #Stxbp2, Gene ID: 81804, NCBI: NP_112388.1, UniProt: Q62753
Catalog #600-401-X16
Price$475
Order / More InfoMunc18 Phospho S515 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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