IL-1 Beta Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | IL-1 Beta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | 100 µg |
| Concentration | 1.0 mg/mL |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was heated to 56° C for 30 minutes. This is an IgG preparation of whole rabbit serum purified by DEAE fractionation. This antibody is primarily directed against mature, 17,000 MW mouse IL-1β and is useful in determining its presence in various assays. The antibody does not recognize human IL-1β or mouse IL-1α. In ELISA formats and other immunoreactive assays, reactivity occurs with rat IL-1β. This antibody will recognize 10% of the non-denatured (native) precursor 31,000 MW mouse IL-1β containing samples but will primarily detect all of the 17,000 MW mature molecule. However, in immunoblot analysis, the usual procedure of heating the sample in SDS with or without reducing agents will facilitate denaturing of the 31,000 MW IL- 1β precursor molecule. Denatured 31,000 precursor IL-1β will be recognized by this antibody. IL-1 beta (also known as Interleukin-1 beta, IL-1β and catabolin) is produced by activated macrophages. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. IL-1β is a monomeric secreted protein that may be released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| Immunogen | This antibody was prepared by repeated immunizations with recombinant mouse IL-1β produced in E.coli. The MW of recombinant mouse IL-1β was 17 kDa. |
| Other Names | rabbit anti-IL-1 beta peroxidase conjugated antibody, rabbit anti-IL-1b HRP conjugated antibody, rabbit anti-Interleukin-1 beta antibody, IL-1β, catabolin, HRP |
| Gene, Accession # | Il1b, Gene ID: 16176, NCBI: CAA28637.1, UniProt: P10749 |
| Catalog # | 210-403-319 |
| Price | $455 |
| Order / More Info | IL-1 Beta Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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