Edit |   |
Antigenic Specificity | Betatrophin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Betatrophin antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Betatrophin antibody is human, mouse and rat reactive. At least three isoforms of Betatrophin are known to exist; this antibody will detect the two largest isoforms. The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3). |
Immunogen | Anti-Betatrophin antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the N-terminus of human Betatrophin. |
Other Names | Betatrophin Antibody, RIFL, TD26, ANGPTL8, PRO1185, PVPA599, Angptl8, Lipasin, Refeeding-induced fat and liver protein, UNQ599/PRO1185, Betatrophin, Angiopoietin-like protein 8, C19orf80 |
Gene, Accession # | ANGPTL8, Gene ID: 55908, NCBI: NP_061157, UniProt: Q6UXH0 |
Catalog # | 600-401-Z57 |
Price | $475 |
Order / More Info | Betatrophin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |