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Antigenic Specificity | IFN beta |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-IFN-beta Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with IFN-beta from other sources has not been determined. Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by "Natural IFN-producing cells" (IPCs) as part of the host immune response and can also inhibit the development of tumors. IFN-beta binding by its receptor results in the activation of the tyrosine kinases Jak1 and Tyk2 and phosphorylation of members of the STAT family of transcription factors, leading to the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis. |
Immunogen | Anti-IFN-beta antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the internal region of human IFN-b. |
Other Names | IFN-beta Antibody, IFB, IFF, IFNB, IFB, Interferon beta, Fibroblast interferon, IFN-beta |
Gene, Accession # | IFNB1, Gene ID: 3456, NCBI: AAC41702, UniProt: P01574 |
Catalog # | 600-401-BT6 |
Price | $475 |
Order / More Info | IFN beta Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |