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Antigenic Specificity | TLR9 |
Clone | 26C593.2 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 100 µg |
Concentration | 1.0 mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-TLR9 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR9 from monkey based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR9 from other sources has not been determined. Anti-TLR9 CD289 Antibody detects human TLR9 CD289. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. By using a BLAST search, a cDNA coding for TLR9 has been identified and subsequently isolated. Gene knockout experiments suggest that TLR9 acts as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. Human and mouse TLR9 share an overall amino-acid identity of 75.5%. TLR9 is highly expressed in spleen. Anti-TLR9 CD289 Antibody is ideal for investigators involved in cytokines and growth factor research. |
Immunogen | TLR9 Antibody was produced in mice prepared repeated immunizations with amino acids corresponding to an internal sequence of human TLR9 isoform A protein. |
Other Names | Toll-like receptor 9 |
Gene, Accession # | TLR9, Gene ID: 54106, NCBI: NP_059138.1, UniProt: Q9NR96 |
Catalog # | 200-301-I31 |
Price | $569 |
Order / More Info | TLR9 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |