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Antigenic Specificity | KLRA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KLRA3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody may cross-react with other LY49 receptors. KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb. |
Immunogen | Anti-KLRA3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the C-terminus of mouse KLRA3. |
Other Names | KLRA3 Antibody, 5E6, Nk2, Nk-2, Ly49c, Nk2.1, NK-2.1, Ly-49c, Ly49C, Killer cell lectin-like receptor 3, 5E6 |
Gene, Accession # | Klra3, Gene ID: 16634, NCBI: AAI32525, UniProt: Q64329 |
Catalog # | 600-401-CF8 |
Price | $475 |
Order / More Info | KLRA3 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |