TACE Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | TACE |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-TACE Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Predicted species reactivity based on immunogen sequence: mouse (94.1%). Cross-reactivity with TACE from other sources has not been determined. TACE Antibody detects TNF-alpha. Tumor-necrosis factor-alpha is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF-alpha; is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-alpha;. TNF-alpha; converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately. TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGFalpha, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP). TACE mRNA is expressed in a variety of human and murine tissues. TACE was selected as one of the few targets in cytokine activation by the Eighth International Conference of the Inflammation Research Association. Anti-TACE antibodies are ideal for investigators involved in Apoptosis and Cytokines and Growth factor research. |
| Immunogen | TACE Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the c-terminus of human TACE. This sequence differs from those of mouse and rat TACE by one amino acid. The immunogen is located within the last 50 amino acids of TACE. |
| Other Names | ADAM17, ADAM18, CD156B, CSVP, NISBD, NISBD1, TACE |
| Gene, Accession # | ADAM17, Gene ID: 6868, NCBI: NP_003174, UniProt: P78536 |
| Catalog # | 600-401-H24 |
| Price | $475 |
| Order / More Info | TACE Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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