Lactate Dehydrogenase Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Lactate Dehydrogenase |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human, rabbit |
| Isotype | n/a |
| Format | IgG fraction |
| Size | 25 µL |
| Concentration | 1.0 mg/ml |
| Applications | ELISA, IF Microscopy, Immunoprecipitation, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-LACTATE DEHYDROGENASE is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Lactate Dehydrogenase [Rabbit Muscle]. BLAST analysis was used to determine that cross reactivity is suggested for both muscle and heart isoforms (LDH-A and LDH-B) from most mammalian species. Lactate dehydrogenase is also known as L-lactate dehydrogenase A chain, LDH-A, LDH muscle subunit and LDH-M. Two isozymes of LDH occur in mammals, LDH-M and LDH-H which come together to form a homotetramer of 36 kDa subunits. Every LDH molecule consists of four subunits, where each subunit is either H or M (based on their electrophoretic properties.) There are, therefore, five LDH isotypes: LDH-1 (4H) - in the heart, LDH-2 (3H1M) - in the reticuloendothelial system, LDH-3 (2H2M) - in the lungs, LDH-4 (1H3M) - in the kidneys and LDH-5 (4M) - in the liver and striated muscle. Usually LDH-2 is the predominant form in the serum. An LDH-1 level higher than the LDH-2 level (a ''flipped pattern'') suggests myocardial infarction (damage to heart tissues releases heart LDH, which is rich in LDH-1, into the bloodstream). LDH complex works to prevent muscle failure and fatigue. LDH can be measured when released during tissue breakdown. LDH appears normally throughout the body, and LDH levels rise with many cancers, so it can be used as a tumor marker but not as a cancer identifier. Anti-Lactate Dehydrogenase Antibody is useful for researcher interested in cancer and metabolism research. |
| Immunogen | This antibody was prepared from whole goat serum produced by repeated immunizations with a full length lactate dehydrogenase protein isolated from rabbit muscle. |
| Other Names | goat anti-Lactate Dehydrogenase Antibody, L-lactate dehydrogenase A chain, LDH-A, LDH muscle subunit, LDH-M |
| Gene, Accession # | LDHA, Gene ID: 100009107, NCBI: 126050, UniProt: P13491 |
| Catalog # | 200-1173S |
| Price | $125 |
| Order / More Info | Lactate Dehydrogenase Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | PubMed: 16314507 // 23460677 // 24989250 // 33269745 // 34081128 // 34081146 |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
Profile of ROCKLAND IMMUNOCHEMICALS INC.