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Antigenic Specificity | Emerin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Emerin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Emerin from other sources has not been determined. Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family that includes proteins such as LAP2 and MAN1. Each family member, including Emerin, has an ~40 amino acid LEM-domains that binds barrier-to-autointegration (BANF1), a conserved chromatin protein that also serves as a host cell component of retroviral integration complexes, including that of HIV. Emerin is anchored at the inner membrane of the nuclear envelope where it binds to nuclear intermediate filaments that are formed by lamin proteins. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. |
Immunogen | Anti-Emerin antibody was prepared from whole rabbit serum produced by repeated immunizations with a 19 amino acid synthetic peptide from near the N-terminus of human Emerin. |
Other Names | Emerin Antibody, STA, EDMD, LEMD5, STA, Emerin |
Gene, Accession # | EMD, Gene ID: 2010, NCBI: NP_000108, UniProt: P50402 |
Catalog # | 600-401-AZ9 |
Price | $475 |
Order / More Info | Emerin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |