DDX41 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | DDX41 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-DDX41 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of DDX41 are known to exist; this antibody will detect both isoforms. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response. |
| Immunogen | Anti-DDX41 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the N-terminus of human DDX41. |
| Other Names | DDX41 Antibody, ABS, ABS, Probable ATP-dependent RNA helicase DDX41, DEAD box protein 41 |
| Gene, Accession # | DDX41, Gene ID: 51428, NCBI: NP_057306, UniProt: Q9UJV9 |
| Catalog # | 600-401-AU5 |
| Price | $475 |
| Order / More Info | DDX41 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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