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Antigenic Specificity | KIRREL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-KIRREL2 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. KIRREL2 antibody is human, mouse and rat reactive. At least five isoforms are known to exist. This antibody is predicted to not cross-react with other members of the KIRREL protein family. KIRREL2, also known as nephrin-like 3, is a type I transmembrane protein belonging to the immunoglobulin superfamily of cell adhesion molecules (1). KIRREL2 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues (1,2). KIRREL2 has been found to be expressed in beta cells of pancreatic islets and is involved in the regulation of both glomerular and neural development (3,4). Downregulation of KIRREL2 is implicated in several proteinuric diseases (4,5). |
Immunogen | Anti-KIRREL2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human KIRREL2. |
Other Names | Kin of irregular chiasm-like protein 2, Kin of IRRE-like protein 2, NEPH3, Nephrin-like protein 3, NLG1, FILTRIN |
Gene, Accession # | KIRREL2, Gene ID: 84063, NCBI: NP_954649, UniProt: Q6UWL6 |
Catalog # | 600-401-CE6 |
Price | $475 |
Order / More Info | KIRREL2 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |