LRRK2/Dardarin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | LRRK2/Dardarin |
| Clone | S231B-34 |
| Host Species | Mouse |
| Reactive Species | human, rat |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 100 µg |
| Concentration | 1mg/mL |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-LRRK2/Dardarin Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. BLAST analysis suggests 81% similarity to mouse, 80% similarity to rat, and <30% identical to LRRK1. LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling. |
| Immunogen | Anti-LRRK2/Dardarin Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 841-960 of human LRRK2. |
| Other Names | Leucine-rich repeat kinase 2, RIP7, PARK8, Dardarin, ROCO 2, RIPK7, Leucine-rich repeat serine/threonine-protein kinase 2, augmented in rheumatoid arthritis 17 |
| Gene, Accession # | LRRK2, Gene ID: 120892, UniProt: Q5S007 |
| Catalog # | 200-301-W59 |
| Price | $485 |
| Order / More Info | LRRK2/Dardarin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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