CD45R (B220) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD45R (B220) |
| Clone | RA3-6B2 |
| Host Species | Rat |
| Reactive Species | human, mouse |
| Isotype | IgG2a kappa |
| Format | phycoerythrin (RPE) conjugate |
| Size | 200 µg |
| Concentration | n/a |
| Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Phycoerythrin conjugated CD45R (B220) Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD45R. Cross reactivity is observed with human and Feline. Cross-reactivity with CD45R from other sources has not been tested. Anti-CD45R is conjugated with PE under optimal conditions and the solution is free of unconjugated PE. CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
| Immunogen | Anti-CD45R (B220) Antibody (Monoclonal) was produced by repeated immunizations with Abelson murine leukemia virus-induced pre-B tumor cells. |
| Other Names | Receptor-type tyrosine-protein phosphatase C, , ukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5 |
| Gene, Accession # | Ptprc UniProt: P06800 |
| Catalog # | 200-508-N84 |
| Price | $349 |
| Order / More Info | CD45R (B220) Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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