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Antigenic Specificity | BCL-B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-Bcl-B Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Bcl-B from other sources has not been determined. Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. |
Immunogen | Anti-Bcl-B antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the N-terminus of human Bcl-B. |
Other Names | Bcl-B Antibody, Boo, Diva, BCL-B, BCLB, Bcl-2-like protein 10, Anti-apoptotic protein NrH, Bcl2-L-10 |
Gene, Accession # | BCL2L10, Gene ID: 10017, NCBI: NP_065129, UniProt: Q9HD36 |
Catalog # | 600-401-Z47 |
Price | $475 |
Order / More Info | BCL-B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |