Edit |   |
---|---|
Antigenic Specificity | APOBEC3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | ELISA, Immunohistochemistry, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-APOBEC3B antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. APOBEC3B antibody is human, mouse and rat reactive. At least three isoforms of APOBEC3B are known to exist; this antibody will detect all three. APOBEC3B antibody may cross-react with APOBEC3D. The Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytosine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 alpha which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection. APOBEC3B has also been shown to be upregulated in several cancers; it is thought that APOBEC3B-catalyzed genomic uracil lesions are responsible for a large proportion of mutations in multiple distinct cancers. |
Immunogen | Anti-APOBEC3B antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the N-terminus of human APOBEC3B. |
Other Names | APOBEC3B Antibody, A3B, ARP4, ARCD3, PHRBNL, APOBEC1L, bK150C2.2, DJ742C19.2Phorbolin-1-related protein, A3B |
Gene, Accession # | APOBEC3B, Gene ID: 9582, NCBI: NP_004891, UniProt: Q9UH17 |
Catalog # | 600-401-Y46 |
Price | $475 |
Order / More Info | APOBEC3B Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |