Interferon Gamma Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityInterferon Gamma
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieschicken
Isotypen/a
FormatProtein A purified
Size25 µL
Concentration1.24 mg/mL
ApplicationsELISA, Western Blot
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DescriptionThis product was protein A purified from monospecific antiserum by chromatography. This antibody is specific for chicken IFN gamma protein. A BLAST analysis was used to suggest cross-reactivity with IFN gamma from chicken based on 100% homology; ring-necked pheasant, turkey, quail, and junglefowl based on 91-97% homology with the immunizing sequence. Cross-reactivity with IFN gamma from other sources has not been determined. Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.
ImmunogenThis protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to 145 amino acids of mature chicken IFN gamma.
Other Namesrabbit anti-Interferon gamma, IFNG, rabbit anti-IFN gamma
Gene, Accession #IFN gamma, Gene ID: 396054, NCBI: NP_990480.1, UniProt: D3GGX1
Catalog #203-401-C41S
Price$125
Order / More InfoInterferon Gamma Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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