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Antigenic Specificity | Interferon Gamma |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | chicken |
Isotype | n/a |
Format | Protein A purified |
Size | 25 µL |
Concentration | 1.24 mg/mL |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This product was protein A purified from monospecific antiserum by chromatography. This antibody is specific for chicken IFN gamma protein. A BLAST analysis was used to suggest cross-reactivity with IFN gamma from chicken based on 100% homology; ring-necked pheasant, turkey, quail, and junglefowl based on 91-97% homology with the immunizing sequence. Cross-reactivity with IFN gamma from other sources has not been determined. Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. |
Immunogen | This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to 145 amino acids of mature chicken IFN gamma. |
Other Names | rabbit anti-Interferon gamma, IFNG, rabbit anti-IFN gamma |
Gene, Accession # | IFN gamma, Gene ID: 396054, NCBI: NP_990480.1, UniProt: D3GGX1 |
Catalog # | 203-401-C41S |
Price | $125 |
Order / More Info | Interferon Gamma Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |