Mimitin Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | Mimitin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 100 µg |
| Concentration | 1 mg/mL |
| Applications | ELISA, IF Microscopy, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Anti-Mimitin Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Mimitin from other sources has not been determined. Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I. |
| Immunogen | Anti-Mimitin antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide from near the C-terminus of human Mimitin. |
| Other Names | Mimitin Antibody, MMTN, B17.2L, mimitin, NDUFA12L, Mimitin, mitochondrial, Myc-induced mitochondrial protein, MMTN |
| Gene, Accession # | NDUFAF2, Gene ID: 91942, NCBI: NP_777549, UniProt: Q8N183 |
| Catalog # | 600-401-CU5 |
| Price | $475 |
| Order / More Info | Mimitin Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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