TNFSF4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityTNFSF4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size100 µg
Concentration1.0 mg/mL
ApplicationsELISA, Immunohistochemistry, IF Microscopy, Western Blot
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DescriptionAnti-TNFSF4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of TNFSF4 are known to exist; this antibody will detect both isoforms. The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFN-gamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
ImmunogenAnti-TNFSF4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid peptide near the C-terminus of human TNFSF4.
Other NamesTNFSF4 Antibody, GP34, CD252, OX4OL, TXGP1, CD134L, OX-40L, Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40L
Gene, Accession #TNFSF4, Gene ID: 7292, NCBI: NP_001284491.1, UniProt: P23510
Catalog #600-401-FL1
Price$475
Order / More InfoTNFSF4 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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