HIF1a Antibody from SICGEN ANTIBODIES

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Antigenic SpecificityHIF1a
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian
Isotypen/a
Formatepitope affinity purified
Size600 µg
Concentration3 mg/ml
ApplicationsWB
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DescriptionRRID: AB_2333145. Goat polyclonal to alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in apoptosis, angiogenesis, energy metabolism, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in tumour angiogenesis, embryonic vascularization, and pathophysiology of ischemic disease. Detects HIF1a in transfected cells and a band of approximately 120 kDa by Western blot in cell lysates.
ImmunogenPurified recombinant peptide derived from within residues 780 aa to the C-terminus of human HIF1a produced in E. coli.
Other Namesalpha subunit (basic helix-loop-helix transcription factor), ARNT interacting protein, basic-helix-loop-helix-PAS protein MOP1, bHLHe78, class E basic helix-loop-helix protein 78, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1a, hypoxia inducible factor 1, hypoxia-inducible factor 1 alpha isoform I.3, hypoxia-inducible factor 1, hypoxia-inducible factor 1-alpha, member of PAS protein 1, member of PAS superfamily 1, MOP1, PASD8, PAS domain-containing protein 8 antibody.
Gene, Accession #Accession: ENSG00000100644
Catalog #AB0112-200
Price320 €
Order / More InfoHIF1a Antibody from SICGEN ANTIBODIES
Product Specific References1. Ferreira JV, Soares AR, Ramalho J, et al. Sci Adv 2022 Mar. PMID: 35333565 2. Martins F, Sacramento JF, Olea E, et al. Antioxidants (Basel) 2021 Aug. PMID: 34439481 3. Rodrigues T, Borges P, Mar L, et al. Pharmacol Res 2020 Sep. PMID:32942016 4. Ferreira JV, Rosa Soares A, Ramalho JS, et al. PLoS One. 2019 Oct. PMID:31613922 5. Rodrigues TDA, PhD Thesis, University of Coimbra, Portugal 2018 6. Fonseca LMO, MSc Thesis, University of Berlin, Germany 2018 7. Rodrigues T, Matafome P, Sereno J, et al. Sci Rep 2017 May 10;7:1698. PMID:28490763 8. Ferreira JV, Soares AR, Ramalho JS, et al. Scientific Reports 5. May 2015. PMID:25958982 9. Sacramento JF, Ribeiro MJ, Rodrigues T, et al. Respir Physiol Neurobiol 2016 Jul. PMID:26993367
SICGEN ANTIBODIES
SICGEN ANTIBODIES
SICGEN ANTIBODIES
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