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Antigenic Specificity | NSP1 (SARS-CoV-2) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | SARS-CoV-2 |
Isotype | n/a |
Format | epitope affinity purified |
Size | 300 µg |
Concentration | 3 mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RRID: AB_2895406. Host translation inhibitor Nsp1 is part of the multifunctional protein replicase polyprotein 1ab that is involved in the transcription and replication of viral RNA. NSP1 inhibits the host translation by interacting with the 40S ribosomal subunit. The nsp1-40S ribosome complex further induces an endonucleolytic cleavage near the 5'UTR of host mRNAs, targeting them for degradation. Therefore, Nsp1 facilitates efficient viral gene expression in infected cells and evasion from host immune response by suppressing host gene expression. In lysates of transfected cells with the plasmid containing the sequence used, detects the fusion protein by Western blot. |
Immunogen | Affinity purified recombinant fusion protein Nsp1 of SARS-CoV-2 produced in E. coli. |
Other Names | Host translation inhibitor, Nsp1 SARS Coronavirus-2 antibody. |
Gene, Accession # | n/a |
Catalog # | AB0385-100 |
Price | 320 € |
Order / More Info | NSP1 (SARS-CoV-2) Antibody from SICGEN ANTIBODIES |
Product Specific References | n/a |