ATXN3 Antibody from SICGEN ANTIBODIES

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Antigenic SpecificityATXN3
Clonepolyclonal
Host SpeciesGoat
Reactive Specieshuman, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian
Isotypen/a
Formatepitope affinity purified, no preservative
Size600 µg
Concentration3 mg/ml
ApplicationsWB
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DescriptionRRID: AB_2895435. Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder. Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. This Ab is similar to AB0089.
ImmunogenPurified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
Other NamesAT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein antibody.
Gene, Accession #Accession: ENSG00000066427
Catalog #AB10089-200
Price320 €
Order / More InfoATXN3 Antibody from SICGEN ANTIBODIES
Product Specific Referencesn/a
SICGEN ANTIBODIES
SICGEN ANTIBODIES
SICGEN ANTIBODIES
Research and Development in Biotechnology Ltd
BIOCANT PARK Nucleo 04, Lt 03
3060-196 Cantanhede PORTUGAL
P: +351 91 9145219
F: +351 21 458 21 89

information@sicgen.pt
Technical Support: technical@sicgen.pt

http://www.sicgen.pt

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