HPV11 E6 Antibody from SICGEN ANTIBODIES

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Antigenic SpecificityHPV11 E6
Clonepolyclonal
Host SpeciesGoat
Reactive SpeciesHuman papilloma viruses type 11
Isotypen/a
Formatepitope affinity purified
Size600 µg
Concentration3 mg/ml
ApplicationsWB
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DescriptionRRID: AB_2333146. Goat polyclonal antibody to HPV11 E6. E6 is one primary oncoprotein of high risk HPV types expressed early in the HPV life cycle. After the host cell is infected viral early promoter is activated and a polycistronic primary RNA containing all six early ORFs is transcribed. This polycistronic RNA then undergoes active RNA splicing to generate multiple isoforms of mRNAs. One of the spliced isoform RNAs, E6, serves as an E7 mRNA to translate E7 protein. HPV genome integrate into host genome by disruption of E2 ORF, preventing E2 repression on E6 and E7. Thus, viral genome integration into host DNA genome increases E6 expression. The E6 protein inactivates the tumour suppressor protein, p53 and promote cellular proliferation and the chance of malignancy. Detects HPV11 E6 recombinant fusion proteins MBP-E6 and GFP-E6 expressed in transfected mammalian cells.
ImmunogenPurified recombinant peptide derived from within residues 65 aa to N-terminal of HPV11 E6 produced in E. coli.
Other Namesn/a
Gene, Accession #n/a
Catalog #AB0107-200
Price300 €
Order / More InfoHPV11 E6 Antibody from SICGEN ANTIBODIES
Product Specific Referencesn/a
SICGEN ANTIBODIES
SICGEN ANTIBODIES
SICGEN ANTIBODIES
Research and Development in Biotechnology Ltd
BIOCANT PARK Nucleo 04, Lt 03
3060-196 Cantanhede PORTUGAL
P: +351 91 9145219
F: +351 21 458 21 89

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