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Product Name | Human Lys-63-Specific Deubiquitinase BRCC36 (BRCC3) Protein |
Description | Human Lys-63-Specific Deubiquitinase BRCC36 (BRCC3) Protein is a recombinant Human protein produced in E. coli using Prokaryotic expression. This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. Gln7-Gly148. N-terminal His tag. Purity > 95%. Calculated MW: 19.8 kDa |
Size | 10 µg, 50 µg, 100 µg, 200 µg |
Concentration | Prior to lyophilization: 200 µg/ml |
Applications | WB, SDS-PAGE |
Other Names | BRCC3, BRCA1/BRCA2-Containing Complex Subunit 3, BRCA1/BRCA2-Containing Complex Subunit 36, Lys-63-Specific Deubiquitinase BRCC36, BRCA1-A Complex Subunit BRCC36, BRISC Complex Subunit BRCC36, CXorf53, BRCC36, C6.1A, BRCA1/BRCA2-Containing Complex, Subunit 3, Chromosome X Open Reading Frame 53, Lys-63-Specific Deubiquitinase, EC 3.1.2.15, EC 3.4.19.-, BRCC3 protein, Protein BRCC3, Human BRCC3 Protein, Human BRCC3, Human protein BRCC3, BRCA1/BRCA2-Containing Complex Subunit 3 protein, Protein BRCA1/BRCA2-Containing Complex Subunit 3, Human BRCA1/BRCA2-Containing Complex Subunit 3 Protein, Human BRCA1/BRCA2-Containing Complex Subunit 3, Human protein BRCA1/BRCA2-Containing Complex Subunit 3, BRCA1/BRCA2-Containing Complex Subunit 36 protein, Protein BRCA1/BRCA2-Containing Complex Subunit 36, Human BRCA1/BRCA2-Containing Complex Subunit 36 Protein, Human BRCA1/BRCA2-Containing Complex Subunit 36, Human protein BRCA1/BRCA2-Containing Complex Subunit 36, Lys-63-Specific Deubiquitinase BRCC36 protein, Protein Lys-63-Specific Deubiquitinase BRCC36, Human Lys-63-Specific Deubiquitinase BRCC36 Protein, Human Lys-63-Specific Deubiquitinase BRCC36, Human protein Lys-63-Specific Deubiquitinase BRCC36, BRCA1-A Complex Subunit BRCC36 protein, Protein BRCA1-A Complex Subunit BRCC36, Human BRCA1-A Complex Subunit BRCC36 Protein, Human BRCA1-A Complex Subunit BRCC36, Human protein BRCA1-A Complex Subunit BRCC36, BRISC Complex Subunit BRCC36 protein, Protein BRISC Complex Subunit BRCC36, Human BRISC Complex Subunit BRCC36 Protein, Human BRISC Complex Subunit BRCC36, Human protein BRISC Complex Subunit BRCC36, CXorf53 protein, Protein CXorf53, Human CXorf53 Protein, Human CXorf53, Human protein CXorf53, BRCC36 protein, Protein BRCC36, Human BRCC36 Protein, Human BRCC36, Human protein BRCC36, C6.1A protein, Protein C6.1A, Human C6.1A Protein, Human C6.1A, Human protein C6.1A, BRCA1/BRCA2-Containing Complex, Subunit 3 protein, Protein BRCA1/BRCA2-Containing Complex, Subunit 3, Human BRCA1/BRCA2-Containing Complex, Subunit 3 Protein, Human BRCA1/BRCA2-Containing Complex, Subunit 3, Human protein BRCA1/BRCA2-Containing Complex, Subunit 3, Chromosome X Open Reading Frame 53 protein, Protein Chromosome X Open Reading Frame 53, Human Chromosome X Open Reading Frame 53 Protein, Human Chromosome X Open Reading Frame 53, Human protein Chromosome X Open Reading Frame 53, Lys-63-Specific Deubiquitinase protein, Protein Lys-63-Specific Deubiquitinase, Human Lys-63-Specific Deubiquitinase Protein, Human Lys-63-Specific Deubiquitinase, Human protein Lys-63-Specific Deubiquitinase, EC 3.1.2.15 protein, Protein EC 3.1.2.15, Human EC 3.1.2.15 Protein, Human EC 3.1.2.15, Human protein EC 3.1.2.15, EC 3.4.19.- protein, Protein EC 3.4.19.-, Human EC 3.4.19.- Protein, Human EC 3.4.19.-, Human protein EC 3.4.19.- |
Gene, Accession, CAS # | BRCC3, Gene ID: 79184, NCBI Accession: NP_001018065.1, NM_001018055.2, NP_001229569.1, NM_001242640.1, NP_077308.1, NM_024332.3, UniProt: P46736 |
Catalog # | abx650811 |
Price | please inquire |
Order / More Info | Human Lys-63-Specific Deubiquitinase BRCC36 (BRCC3) Protein from ABBEXA LTD |
Product Specific References | n/a |
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