YM-08 from ABBEXA LTD
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| Product Name | YM-08 |
| Description | YM-08 is a small molecule. YM-08 is a Heat Shock Protein 70 (Hsp70) inhibitor that is blood-brain barrier permeable. YM-08 is a neutral derivative of the Hsp70 inhibitor MKT-077. MKT-077 reduces tau levels in cellular models, but it doesn?t penetrate the blood brain barrier. Although YM-08 was somewhat less effective than MKT-077 in anti-tau and anticancer assays, it selectively reduced pathogenic tau in brain slices, which MKT-077 did not. Furthermore, YM-08 was not retained in the kidney leading one to speculate that it would not have the nephrotoxicity that was a problem for MKT-077 in clinical trials. Looking for more information on HSP70? Visit our new HSP70 Scientific Resource Guide at http://www.HSP70.com. Purity > 99% (HPLC). MW: 367.49 g/mol |
| Size | 10 mg, 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | (2Z,5E)-3-ethyl-5-(3-methyl-1,3-benzothiazol-2-ylidene)-2-(pyridin-2-ylmethylidene)-1,3-thiazolidin-4-one, YM8, YM08 |
| Gene, Accession, CAS # | n/a |
| Catalog # | abx076595 |
| Price | please inquire |
| Order / More Info | YM-08 from ABBEXA LTD |
| Product Specific References | n/a |
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