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Product Name | Afutuzumab ELISA Kit |
Description | Afutuzumab ELISA Kit is a quantitative ELISA kit for detection of Afutuzumab. Afutuzumab is a monoclonal antibody that targets the CD20 antigen expressed on the surface of pre-B and mature B lymphocytes. Upon binding to CD20, obinutuzumab mediates B-cell lysisthrough (1) engagement of immune effector cells (2) by directly activating intracellular death signaling pathways (direct cell death), and/or (3) activation of the complement cascade. The immune effector cell mechanisms include antibody-dependent cellular cytotoxicity (ADCC) and antibodydependent cellular phagocytosis.As an antibody with reduced fucose content, obinutuzumab induces greater ADCC activity than rituximab in vitro using human cancer cell lines. Afutuzumab also demonstrated an increased ability to induce direct cell death when compared to rituximab. Afutuzumab binds to Fc?RIII using purified proteins with a higher affinity than rituximab. Afutuzumab and rituximab bind with similar affinity to overlapping epitopes on CD20. Range: 0.31 ?g/ml - 5 ?g/ml. Sensitivity: 0.16 ?g/ml |
Size | 96 tests, |
Concentration | n/a |
Applications | ELISA |
Other Names | Afutuzumab, GA101,RG7159,RO5072759,949142-50-1, ELISA Afutuzumab, ELISA for Afutuzumab, ELISA kit Afutuzumab, ELISA kit for Afutuzumab, Enzyme-linked immunosorbent assay Afutuzumab, Human Afutuzumab, Afutuzumab ELISA, Afutuzumab ELISA kit, Afutuzumab Enzyme-linked immunosorbent assay, Human Afutuzumab ELISA, Human Afutuzumab ELISA kit, ELISA GA101,RG7159,RO5072759,949142-50-1, ELISA for GA101,RG7159,RO5072759,949142-50-1, ELISA kit GA101,RG7159,RO5072759,949142-50-1, ELISA kit for GA101,RG7159,RO5072759,949142-50-1, Enzyme-linked immunosorbent assay GA101,RG7159,RO5072759,949142-50-1, Human GA101,RG7159,RO5072759,949142-50-1, GA101,RG7159,RO5072759,949142-50-1 ELISA, GA101,RG7159,RO5072759,949142-50-1 ELISA kit, GA101,RG7159,RO5072759,949142-50-1 Enzyme-linked immunosorbent assay, Human GA101,RG7159,RO5072759,949142-50-1 ELISA, Human GA101,RG7159,RO5072759,949142-50-1 ELISA kit |
Gene, Accession, CAS # | n/a |
Catalog # | abx395063 |
Price | please inquire |
Order / More Info | Afutuzumab ELISA Kit from ABBEXA LTD |
Product Specific References | n/a |
U.S. Office
118 Eldridge Rd, Suite C,
Sugar Land, TX 77478 USA
Telephone: +1 832 327 7413
Netherlands Office
Abbexa BV
Wattstraat 54 2723 RD,
Zoetermeer,Netherlands
Telephone: +44 (0) 1223 755950