CD73 Inhibitor Screening Kit from ACROBIOSYSTEMS USA
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| Product Name | CD73 Inhibitor Screening Kit |
| Description | 5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene. CD73 commonly serves to convert AMP to adenosine. Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rare allelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain. |
| Size | 96 tests |
| Concentration | n/a |
| Applications | This kit is developed for screening inhibitors of CD73. |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | EP-166-96tests |
| Price | $600 |
| Order / More Info | CD73 Inhibitor Screening Kit from ACROBIOSYSTEMS USA |
| Product Specific References | n/a |
ACROBIOSYSTEMS USA
ACROBIOSYSTEMS USA
1 Innovation Way
Newark DE 19711
P: +1 800-810-0816
F: +1 888-377-6111
info@acrobiosystems.com
http://www.acrobiosystems.com
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ACROBIOSYSTEMS China
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Beijing, 100176 China
Tel: +86 400-685-2052
Fax: +86 10-5885-0566
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