SARS-CoV-2 Spike Trimer Protein (N501Y, D614G), His Tag (MALS verified) from ACROBIOSYSTEMS USA
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| Product Name | SARS-CoV-2 Spike Trimer Protein (N501Y, D614G), His Tag (MALS verified) |
| Description | SARS-CoV-2 S protein (N501Y, D614G), His Tag (SPN-C52Hp) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (N501Y, D614G)). The N501Y/D614G mutations were identified in multiple SARS-CoV-2 variants which emerged in the United Kingdom (known as B.1.1.7, 20B/501Y.V1 or VOC 202012/01), South Africa(known as B.1.351 or 20C/501Y.V2), and Brazil (Known as P.1). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 138.0 kDa. The protein migrates as 170-220 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity: 95% |
| Size | 50ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | recombinant protein |
| Gene, Accession, CAS # | Accession: QHD43416.1 (N501Y, D614G) |
| Catalog # | SPN-C52Hp-50ug |
| Price | $450 |
| Order / More Info | SARS-CoV-2 Spike Trimer Protein (N501Y, D614G), His Tag (MALS verified) from ACROBIOSYSTEMS USA |
| Product Specific References | n/a |
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