Biotinylated SARS-CoV-2 S protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) trimer, His, Avitag™ (MALS verified) from ACROBIOSYSTEMS USA

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Product NameBiotinylated SARS-CoV-2 S protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) trimer, His, Avitag™ (MALS verified)
DescriptionBiotinylated SARS-CoV-2 S protein trimer, His, Avitag (SPN-C82E5) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively. The HV69-70del/ Y144del/ N501Y/ A570D/ D614G/ P681H/ T716I/ S982A/ D1118H/ mutations were identified in the SARS-CoV-2 Alpha variant (Pango lineage: B.1.1.7; other names: 20I/501Y.V1 or VOC 202012/01). This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 139.4 kDa. The protein migrates as 160-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity: 95%
Size200ug
Concentrationn/a
Applicationsn/a
Other Namesrecombinant protein
Gene, Accession, CAS #Accession: QHD43416.1
Catalog #SPN-C82E5-200ug
Price$2420
Order / More InfoBiotinylated SARS-CoV-2 S protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H, T716I, S982A, D1118H) trimer, His, Avitag™ (MALS verified) from ACROBIOSYSTEMS USA
Product Specific Referencesn/a
ACROBIOSYSTEMS USA
ACROBIOSYSTEMS USA
ACROBIOSYSTEMS USA
1 Innovation Way
Newark DE 19711
P: +1 800-810-0816
F: +1 888-377-6111

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