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Product Name | BMS 182874 hydrochloride |
Description | BMS 182874 hydrochloride is a potent, selective and competitive antagonist of ET-A endothelin receptors. It exhibits a 1000-fold selectivity for ET-A over ET-B receptors, inhibiting endothelin-1 radioligand binding to ET-A and ET-B with Ki of 61 nM and >50 µM, respectively. In vitro, BMS 182874 inhibits endothelin-1 induced calcium mobilization with KB of 140 nM1. BMS 182874 is orally bioavailable and active in vivo1,2. Synthetic. Purity >99%. MW: 381.88 |
Size | 10 mg |
Concentration | 100 nM - 10 µM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 1215703-04-0 |
Catalog # | B-500 |
Price | please inquire |
Order / More Info | BMS 182874 hydrochloride from ALOMONE LABS |
Product Specific References | n/a |
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