XBP1 ELISA Kit from ANTIBODIES-ONLINE GmbH
Search, find, compare suppliers for XBP1 ELISA Kit products.
| Edit | |
|---|---|
| Product Name | XBP1 ELISA Kit |
| Description | Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of XBP1 in rat tissue homogenates, cell lysates. Target Information: This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008]. |
| Size | 5 x 96 tests |
| Concentration | n/a |
| Applications | ELISA |
| Other Names | TREB5|XBP-1|XBP2|X-box-binding protein 1|tax-responsive element-binding protein 5|X-box binding protein 1|XBP1|D11Ertd39e|TREB-5|tax-responsive element-binding protein 5 homolog|cb918|id:ibd1195|trebf|wu:fb02h05|wu:fb63f10|xbp1a|xbp1b|X-box binding protein 1B|HTF|hepatocarcinogenesis-related transcription factor|xXBP1|X-box binding protein 1 L homeolog|xbp1.L|XBP1P1|XBPP1|X-box binding protein 1 pseudogene 1|X-box binding protein pseudogene 1 |
| Gene, Accession, CAS # | Gene ID: 289754 |
| Catalog # | ABIN7060588 |
| Price | $3780 |
| Order / More Info | XBP1 ELISA Kit from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155
info@antibodies-online.com
Orders: orders@antibodies-online.com
Technical Support: support@antibodies-online.com
https://www.antibodies-online.com
Profile of ANTIBODIES-ONLINE GmbH