SAHA (Vorinostat ) from ARBOR ASSAYS, INC.
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| Product Name | SAHA (Vorinostat ) |
| Description | SAHA (suberoylanilide hydroxamic acid, Vorinostat, Zolinza™) is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) is 1 uM for Sirt1, 25 uM for Sirt2, and 50 uM for Sirt3. The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. SAHA inhibits class I and class II HDACs at around 50 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 uM. |
| Size | 250 mg |
| Concentration | 250 mg |
| Applications | Activator or Inhibitor |
| Other Names | suberoylanilide hydroxamic acid, Vorinostat, Zolinza |
| Gene, Accession, CAS # | n/a |
| Catalog # | P004-250MG |
| Price | $276.86 |
| Order / More Info | SAHA (Vorinostat ) from ARBOR ASSAYS, INC. |
| Product Specific References | n/a |
ARBOR ASSAYS, INC.
ARBOR ASSAYS, INC.
1514 Eisenhower Place
Ann Arbor MI 48108-3284
P: 734-677-1774
F: 734-661-1884
info@ArborAssays.com
http://www.arborassays.com
Direct Order Fax Line: 734-677-6860
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