IBMX from ARBOR ASSAYS, INC.
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| Product Name | IBMX |
| Description | IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) with IC50s from 7 to 50 µM for PDE1-5, PDE7, and PDE11. PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP levels, activating cyclic-nucleotide-regulated protein kinases. Methylxanthines, including IBMX, caffeine, and theophylline, bind adenosine receptors, typically antagonizing the suppressive effects of natural agonists. Suppresses alpha-adrenoceptor-mediated 5-HT release from neuroendocrine epithelial cells (IC50 = 1.3 µM). |
| Size | 100 mg |
| Concentration | 100 mg |
| Applications | Activator or Inhibitor |
| Other Names | PDE inhibitor |
| Gene, Accession, CAS # | n/a |
| Catalog # | P019-100MG |
| Price | $51.23 |
| Order / More Info | IBMX from ARBOR ASSAYS, INC. |
| Product Specific References | n/a |
ARBOR ASSAYS, INC.
ARBOR ASSAYS, INC.
1514 Eisenhower Place
Ann Arbor MI 48108-3284
P: 734-677-1774
F: 734-661-1884
info@ArborAssays.com
http://www.arborassays.com
Direct Order Fax Line: 734-677-6860
Profile of ARBOR ASSAYS, INC.