EX-527 from ARBOR ASSAYS, INC.
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| Product Name | EX-527 |
| Description | EX-527 is a cell-permeable, selective inhibitor of SIRT1 (IC50 = 98 nM in vivo, 38nM in vitro) that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 20 uM, 49 uM, > 100 uM and > 100 uM for SIRT2, SIRT3, HDAC and NADase respectively). EX-527 has been used to investigate the relationship between SIRT1-mediated deacetylation of p53, p53 activity, and cell survival following DNA damage. |
| Size | 5 mg |
| Concentration | 5 mg |
| Applications | Activator or Inhibitor |
| Other Names | SIRT 1 inhibitor |
| Gene, Accession, CAS # | n/a |
| Catalog # | P005-5MG |
| Price | $115.54 |
| Order / More Info | EX-527 from ARBOR ASSAYS, INC. |
| Product Specific References | n/a |
ARBOR ASSAYS, INC.
ARBOR ASSAYS, INC.
1514 Eisenhower Place
Ann Arbor MI 48108-3284
P: 734-677-1774
F: 734-661-1884
info@ArborAssays.com
http://www.arborassays.com
Direct Order Fax Line: 734-677-6860
Profile of ARBOR ASSAYS, INC.