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Product Name | Recombinant Human SLAMF4 (CD244/2B4)-Fc Chimera (carrier-free) |
Description | SLAMF4, also known as 2B4 and CD244, is one of the members of the CD2 subfamily. It is expressed on NK cells, monocytes, basophils, TCR γ/δ T cells, and a subset of CD8 T cells. Engagement of SLAMF4 by antibodies or a natural ligand, such as CD48, leads to tyrosine phosphorylation of SLAMF4, cell-mediated cytotoxicity and IFN-γ secretion by NK cells. Except CD48 ligation, SLAMF4-mediated non-MHC-restricted cell cytotoxicity is also dependent on others NCRs, such as NKp46 (NCR1/CD335). However, |
Size | 10 µg |
Concentration | n/a |
Applications | BA |
Other Names | SLAMF4, SLAM family member 4, 2B4, Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NAIL, NK cell type I receptor protein 2B4, NKR2B4, h2B4, signaling lymphocytic activation molecule 4, CD244 |
Gene, Accession, CAS # | Gene ID: 51744 |
Catalog # | 784202 |
Price | $112 |
Order / More Info | Recombinant Human SLAMF4 (CD244/2B4)-Fc Chimera (carrier-free) from BIOLEGEND |
Product Specific References | n/a |