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Product Name | Recombinant Human BAFF (carrier-free) |
Description | BAFF is a TNF-α cytokine member (a type II membrane protein) that acts in both a membrane-bound form and soluble cytokine form. The extracellular domain of BAFF shows high homology with APRIL. The soluble form is derived by cleavage in a furin consensus site. In human neutrophils treated with G-CSF, BAFF is processed intracellularly by a furin-type convertase. BAFF acts mainly as a soluble trimer and binds to three receptors with decreasing affinity in the following order: BAFFR > TACI > BCMA. M |
Size | 25 µg |
Concentration | n/a |
Applications | BA |
Other Names | B cell activating factor belonging to the TNF family (BAFF), B lymphocytes stimulator (BLyS), TNF- and APOL-related leucocyte expressed ligand 1(TALL1), TNF homolog that activates apoptosis, NKFB, JNK (THANK), TNF13B, CD257 |
Gene, Accession, CAS # | Gene ID: 10673 |
Catalog # | 559604 |
Price | $265 |
Order / More Info | Recombinant Human BAFF (carrier-free) from BIOLEGEND |
Product Specific References | PubMed: 30314758 |