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Product Name | Recombinant Human TPO (carrier-free) |
Description | TPO is a key regulator of megakaryocytopoiesis and thrombopoiesis. TPO binds to its receptor, the cellular homologue of the myeloproliferative leukemia virus oncogene (c-Mpl), and stimulates the proliferation and maturation of megakaryocytes. MPL does not possess kinase activity, thus the receptor associates with intracytoplasmic tyrosine kinases, janus kinase 2 (JAK2), for signal transduction. JAK2 is also important for MPL stability and cell-surface expression. TPO is able to promote the surv |
Size | 100 µg |
Concentration | n/a |
Applications | BA |
Other Names | Megakaryocyte Colony Stimulating Factor (MKCSF), Myeloproliferative leukemia virus oncogene ligand (Mpl-ligand), Megakaryocyte growth and development factor (MGDF), THPO |
Gene, Accession, CAS # | Gene ID: 7066 |
Catalog # | 763706 |
Price | $996 |
Order / More Info | Recombinant Human TPO (carrier-free) from BIOLEGEND |
Product Specific References | n/a |