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Product Name | Recombinant Human TNFRSF10B (TRAIL R2)-Fc Chimera CF |
Description | TNFRSF10B, also called TRAIL R2 and DR5, is a member of the TNF receptor superfamily. It contains a cysteine-rich extracellular domain, a transmembrane domain and an intracellular death domain, which mediates interactions between death receptor and death domain-containing adaptor proteins. When the trimeric ligand TRAIL (TNFSF10) is bound, homotrimer TNFRSF10B interacts with the adaptor protein Fas-associated death domain (FADD), in turn recruits caspase-8 and assembles a death-inducing signalin |
Size | 100 µg |
Concentration | n/a |
Applications | BA |
Other Names | Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), TRAIL receptor 2, Death receptor 5 (DR5), CD262, KILLER, TRICK2 |
Gene, Accession, CAS # | Gene ID: 8795 |
Catalog # | 770606 |
Price | $335 |
Order / More Info | Recombinant Human TNFRSF10B (TRAIL R2)-Fc Chimera CF from BIOLEGEND |
Product Specific References | n/a |