Autophagy Detection Probe Green from BIOLEGEND

Autophagy is a highly conserved degradation process that removes unnecessary or dysfunctional components through a lysosome-dependent regulated mechanism. In the absence of cellular stress, autophagy serves as a house-keeping function, removing damaged organelles and cellular components. Insufficient autophagy leads to accumulation of damaged cells and aging. When activated during cellular stress or starvation, the breakdown of cellular components promotes cellular survival by maintaining cellular energy levels. Autophagy Detection Probe Green employs a specific autophagosome marker to analyze the activity of autophagy. The assay is optimized for direct detection of autophagy in live cells.