Recombinant Rat RANKL (TRANCE, TNFSF11) (carrier-free) from BIOLEGEND
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| Product Name | Recombinant Rat RANKL (TRANCE, TNFSF11) (carrier-free) |
| Description | The RANKL gene encodes a type II membrane protein of 316 amino acids with a predicted molecular mass of 35 kD. RANKL is cleaved to produce a soluble form with biological activity. The shedding of membrane-bound RANKL appears to be mediated by expression of MMP14 and ADAM10. Suppression of MMP14 in primary osteoblasts increases membrane-bound RANKL and promotes osteoclastogenesis in cocultures with macrophages. Therefore, RANKL shedding seems to be an important process that downregulates local os |
| Size | 25 µg |
| Concentration | n/a |
| Applications | BA |
| Other Names | Tumor necrosis factor ligand superfamily, member 11 (TNFSF11), Osteoprotegerin ligand (OPGL), Receptor activator of NF-kappa-B ligand (RANKL), TNF-related activation-induced cytokine (TRANCE), Osteoclast differentiation factor (ODF), CD254 |
| Gene, Accession, CAS # | Gene ID: 117516 |
| Catalog # | 779204 |
| Price | $288 |
| Order / More Info | Recombinant Rat RANKL (TRANCE, TNFSF11) (carrier-free) from BIOLEGEND |
| Product Specific References | n/a |
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