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Product Name | Human Neuropilin-2 / NRP2 Protein |
Description | Neuropilin-1 (Npn-1, previously known as neuropilin) and Neuropilin-2 (previously known as Npn-1-related molecule) are type I transmembrane Proteins that bind distinct members of the class III secreted semaphorin subfamily that are implicated in repulsive axon guidance. Neuropilin extracellular domains contain two CUB (complement-binding) domains, two domains with homology to coagulation factors V and VIII, and a MAM (meprin) domain. In the absence of ligands, neuropilins can form homo- and hetero-oligomers via their MAM domains. Expression in developing neurons of the central and peripheral nervous systems is somewhat overlapping but distinct. Npn-1 and Npn-2 are also receptors for VEGF165 on endothelial and tumor cells. Purity 95.00%. MW: 97.0 kDa |
Size | 100 ug, 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Neuropilin-2,NRP2,VEGF165R2,Neuropilin2,Vascular endothelial cell growth factor 165 receptor 2 |
Gene, Accession, CAS # | NCBI: NP_957718.1 |
Catalog # | orb1176558 |
Price | $633 |
Order / More Info | Human Neuropilin-2 / NRP2 Protein from BIORBYT LTD. |
Product Specific References | n/a |
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