Cynomolgus / Rhesus macaque CTLA-4 Protein from BIORBYT LTD.
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| Product Name | Cynomolgus / Rhesus macaque CTLA-4 Protein |
| Description | CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a Protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The Protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory Protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on Antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. Fusion Proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis. Purity 90.00%. MW: 39.9 kDa |
| Size | 1 mg, 200 ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CTLA4,CD152 |
| Gene, Accession, CAS # | NCBI: XP_005574071.1 |
| Catalog # | orb257376 |
| Price | $1238 |
| Order / More Info | Cynomolgus / Rhesus macaque CTLA-4 Protein from BIORBYT LTD. |
| Product Specific References | n/a |
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