Human CD46 Protein from BIORBYT LTD.
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| Product Name | Human CD46 Protein |
| Description | Complement regulatory Protein CD46 is also known as membrane Cofactor Protein (MCP), is a type I membrane Protein and is a regulatory part of the complement system. CD46 is expressed by all cells except erythrocytes. MCP acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue, and also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. In T-cells by binding to CD46, A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype. Defects in CD46 are a cause of susceptibility to hemolytic uremic syndrome atypical type 2 (AHUS2). Purity 90.00%. MW: 33.6 kDa |
| Size | 50 ug, 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | CD46,AHUS2,MCP,MIC10,TLX,TRA2.10 |
| Gene, Accession, CAS # | n/a |
| Catalog # | orb257285 |
| Price | $533 |
| Order / More Info | Human CD46 Protein from BIORBYT LTD. |
| Product Specific References | n/a |
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