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Product Name | Cynomolgus B7-H2 / ICOSLG Protein |
Description | ICOS ligand (ICOSLG) is also known as B7 homolog 2 (B7-H2), B7-related Protein 1 (B7RP-1) and CD Antigen CD275, which belongs to the immunoglobulin superfamily and BTN/MOG family. ICOSLG contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. Isoform 1 is widely expressed, while isoform 2 is detected only in lymph nodes, leukocytes and spleen. B7-H2 is ligand for the T-cell-specific cell surface receptor ICOS. B7-H2 acts as a costimulatory signal for T-cell proliferation and cytokine secretion and induces also B-cell proliferation and differentiation into plasma cells. B7-H2 could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. Purity 90.00%. MW: 28.5 kDa |
Size | 100 ug, 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | ICOSLG,B7-H2,B7H2,B7RP-1,B7RP1,CD275,GL50,ICOS-L,ICOSL,LICOS,ICOS ligand |
Gene, Accession, CAS # | NCBI: XP_005548617.1 |
Catalog # | orb612100 |
Price | $510 |
Order / More Info | Cynomolgus B7-H2 / ICOSLG Protein from BIORBYT LTD. |
Product Specific References | n/a |
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