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Product Name | Biotinylated Cynomolgus B7-H7 / HHLA2 Protein, His, |
Description | B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members. Purity 90.00%. MW: 39.1 kDa |
Size | 25 ug, 200 ug |
Concentration | n/a |
Applications | n/a |
Other Names | B7-H7,HHLA2,B7 Homolog 7 |
Gene, Accession, CAS # | NCBI: XP_005548285.1 |
Catalog # | orb1570940 |
Price | $587 |
Order / More Info | Biotinylated Cynomolgus B7-H7 / HHLA2 Protein, His, from BIORBYT LTD. |
Product Specific References | n/a |
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