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Product Name | Vericiguat |
Description | A stimulator of sGC; stimulates the formation of cGMP in CHO cells expressing recombinant rat sGC in the absence and presence of SNAP (EC50s = 1,005 and 39 nM, respectively), an effect that can be reversed by ODQ; inhibits phenylephrine-induced contractions in isolated rabbit saphenous artery rings, rabbit aortic rings, and canine femoral vein rings (IC50s = 798, 692, and 3,072 nM, respectively); decreases the coronary perfusion pressure in isolated perfused rat hearts; decreases proteinuria and increases survival in an (mRenR2)27 transgenic rat model of hypertension at 3 or 10 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BAY-1021189|MK-1242 |
Gene, Accession, CAS # | CAS: 1350653-20-1 |
Catalog # | 35253-5 |
Price | $66.00 |
Order / More Info | Vericiguat from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |