Vericiguat from CAYMAN CHEMICAL COMPANY

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Product NameVericiguat
DescriptionA stimulator of sGC; stimulates the formation of cGMP in CHO cells expressing recombinant rat sGC in the absence and presence of SNAP (EC50s = 1,005 and 39 nM, respectively), an effect that can be reversed by ODQ; inhibits phenylephrine-induced contractions in isolated rabbit saphenous artery rings, rabbit aortic rings, and canine femoral vein rings (IC50s = 798, 692, and 3,072 nM, respectively); decreases the coronary perfusion pressure in isolated perfused rat hearts; decreases proteinuria and increases survival in an (mRenR2)27 transgenic rat model of hypertension at 3 or 10 mg/kg
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesBAY-1021189|MK-1242
Gene, Accession, CAS #CAS: 1350653-20-1
Catalog #35253-5
Price$66.00
Order / More InfoVericiguat from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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